The Friendly Confines has been the site of such historic moments as:
- Babe Ruth's "called shot," when Ruth allegedly pointed to a bleacher location during Game 3 of the 1932 World Series ... Ruth then hit Charlie Root's next pitch for a homer.
- Ernie Banks' 500th career home run May 12, 1970, vs. Atlanta's Pat Jarvis
- Kerry Wood's 20-strikeout affair in 1998.
- Sammy Sosa's 60th home runs in 1998, 1999 and 2001. (Number 500 against the Cubs in 2007 at Texas)
- The 1947, 1962 and 1990 All-Star Games.
- The Wrigley Field bleachers and scoreboard were constructed in 1937 when the outfield area was renovated to provide improved and expanded seating ... the original scoreboard remains intact.
- Originally known as Weeghman Park, Wrigley Field was built on the grounds once occupied by a seminary.
- The original vines were purchased and planted by Bill Veeck in September 1937 ... Veeck strung bittersweet from the top of the wall to the bottom, then planted the ivy at the base of the wall.